Granules with MBCP™ Technology for high quality bone.
MBCP™ is a balanced combination of 60% Hydroxyapatite and 40% β-TCP for optimal bone regeneration with over 30 years of clinical background. The macropores (300-600 µm) provide an ideal surface for cell adhesion while micropores (˂10 µm) attract growth factors and proteins crucial for bone regeneration.
• Hydroxyapatite is the closest synthetic equivalent to human bone mineral (biological apatite crystals), is biocompatible and bioactive “in-vivo”
• TCP is recognized to have great bioactivity, fast dissolution to promote the ionic exchange (Calcium and Phosphorus ions).
• Macro-pores guide bone forming cells into the MBCP™ structure, 100% regeneration into new lamellar or haversian bone, providing a newly vascularized and mineralized bone architecture.
MBCP™ is safe, completely synthetic bone graft manufactured processed for Keystone Dental by Biomatlante using the proprietary MBCP™ Technology to promote and regenerate high quality bone. This technology has been at the center of extensive clinical and scientific studies over the last 30 years (more than 600 publications).
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• The micro macroporous biphasic calcium concept for bone reconstruction and tissue engineering. Daculsi G., Jegoux F., Layrolle P.; In advanced Biomaterials: Fundamentals, Processing and Applications, John WILEY & Sons USA, in press 2008-1.
• Elaboration conditions influence physicochemical properties and in vivo bioactivity of macroporous biphasic calcium phosphate ceramics. Gauthier O., Bouler JM., Aguado E., Legeros RZ., Pilet P., Daculsi G. Journal of materials science : materials in medicine 10 (1999) 199-20
• Efficacy and performance of bone substitute for bone reconstruction I place of allograft and autograft. Daculsi G., Malard O., Goyenvalle E., ITBM RBM 26 (2005) 218-222
• A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cellinduced bone formation. Arinzeh TL, Tran T, McAlary J, Daculsi G. Biomaterials. 2005
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• Tissue response to biphasic calcium phosphate ceramic with different ratios of HA/β-TCP in periodontal osseous defects Nery EB, LeGeros RZ, Lynch KL, Kelvin L (1992) J Periodontol 63:729-735.
• Formation of Carbonate-Apatite Crystals After Implantation of Calcium Phosphate Ceramics. G. Daculsi, R.Z. Le Geros, M. Heughebaert and I. Barbieux; Calcif Tissue Int (1990) 46:20-27
• Transformation of biphasic calcium phosphate ceramics in vivo: ultrastructural and physicochemical characterization. Daculsi G., Legeros R.Z, Nery E., Lynch K., Kerebel B., Journal of Biomedical Materials Research, vol 23, 883-894 (1989).
• Histological assessment of periodontal osseous defects following implantation of hydroxyapatite and biphasic calcium phosphate ceramics: a case report Ellinger RF, Nery EB, Lynch KL (1986) J Periodont Restor Dent 3:223.